Brain activity between seizures informs potential treatment for childhood absence epilepsy
https://www.mymedistore.com/ Absence seizures cause a short period of "blanking out" or staring into space, due to brief abnormal electrical activity in the brain. In this new study, even after the seizures in the mice were treated, the abnormality that was previously seen between seizures persisted. This may provide a potential explanation for why some children with absence epilepsy may have continued deficits in cognitive performance, despite successful treatment of their seizures. EEG, a test that measures electrical activity in the brain, has thus far been primarily used to detect seizures, rather than identifying cognitive impairment. This study suggests that looking at EEG activity between seizures could help physicians diagnose and monitor cognitive and other attentional deficits in epilepsy. Jeffrey Noebels and his team at Baylor College of Medicine in Houston, Texas used two genetic mouse models of absence epilepsy and compared them to unaffected mice. They an...